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About PRF

Platelet Rich Fibrin (PRF)

Aging changes in the skin can be reduced by increasing collagen and hyaluronic acid. Blood products contain many growth factors that help stimulate skin cell growth, which leads to more collagen and hyaluronic acid. This is why PRP (Platelet-Rich Plasma) is popular in skin rejuvenation. People who received PRP saw thicker collagen due to higher levels of certain proteins that help maintain healthy skin.

 

Fluid PRF (Platelet-Rich Fibrin) is even more effective than PRP because it encourages more skin cell movement and collagen production, with a natural structure that acts like a support system for growth factors. Studies have shown that PRF injections alone can restore volume under the eyes, even skin tone, and reduce fine lines. When combined with hyaluronic acid, PRF can help the skin retain moisture and improve collagen growth. Unlike traditional treatments like chemical peels or botox, PRF is safer and more affordable because it uses the body’s own cells.

How Does PRF Compare to Other Fillers?

PRF is often compared to other fillers like Sculptra, hyaluronic acid, and Radiesse. Here’s a breakdown of how these treatments differ:

PRF Chart Comparison

Each treatment has unique benefits:

  • PRF and PRP are natural options derived from your own blood, which can be ideal for people looking for an organic approach to anti-aging. They are best for rejuvenating the skin gradually without adding dramatic volume.

  • Sculptra stimulates collagen production, similar to PRF, but it lasts longer and is suitable for areas needing more volume.

  • Hyaluronic Acid fillers provide instant results, are versatile, and are commonly used for areas like the lips and under-eye hollows.

  • Radiesse provides both volume and collagen stimulation and is often used for deeper wrinkles or to contour the face.

 

In terms of Sculptra and hyaluronic acid comparison, Sculptra works gradually by encouraging collagen production, while hyaluronic acid fillers give immediate volume.

Benefits of PRF

PRF has several benefits that make it appealing for aesthetic procedures:

  1. Natural Treatment: Since PRF comes from your own blood, it’s a natural option without synthetic ingredients, reducing the risk of allergic reactions.

  2. Collagen Stimulation: PRF works by stimulating the body’s natural collagen production, which helps improve skin texture and reduce fine lines over time.

  3. Gradual, Long-Lasting Results: While PRF doesn’t provide immediate volume like some fillers, the results develop gradually and can last 3-6 months. This makes it a good option for people who want a subtle, natural improvement.

  4. Improves Skin Quality: PRF can improve skin texture, tone, and elasticity, creating a fresher, more youthful appearance.

PRF Under Eyes

One popular area for PRF treatment is under the eyes. As people age, they often lose volume in this area, leading to a hollow or dark appearance. PRF injections under the eyes can help by adding subtle volume and improving skin quality.

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PRF is particularly effective for this delicate area because it stimulates collagen without creating an unnatural “filled” look. Additionally, since PRF is a natural treatment, it’s generally well-tolerated in sensitive areas like under the eyes.

PRF vs. PRP: What’s the Difference?

Although PRF and PRP (Platelet-Rich Plasma) are similar, there are a few key differences:

  • Preparation Process: PRF is spun at a lower speed in the centrifuge, allowing it to retain more white blood cells, stem cells, and fibrin.

  • Release of Growth Factors: PRF releases growth factors more slowly over time, which can provide a longer-lasting effect.

  • No Additives: PRF doesn’t contain anticoagulants, so it clots naturally, allowing for slower, sustained release.

 

This difference means that PRF may be more effective for long-term collagen stimulation, while PRP tends to work faster but with shorter-lasting results.

How Long Does PRF Last?

PRF results can last anywhere from 3 to 6 months, depending on factors like skin type, area treated, and individual responses. Because PRF stimulates collagen production, some effects may continue even after the initial results fade, as collagen builds up in the treated area.

 

For optimal results, many people choose a series of treatments, with sessions spaced about 4-6 weeks apart. This layering of treatments can enhance collagen production and extend the effects of PRF.

PRP and PRF Cost

The cost of PRF treatments can vary widely based on location and provider, but on average, it may cost between $500 and $1,500 per session. This is similar to PRP, which generally ranges from $500 to $2,000 per treatment.

 

Since PRF is typically administered in multiple sessions, it’s essential to consider the cost of a series of treatments if you want to achieve the best possible results. Providers often offer package deals, which can make it more affordable to commit to several sessions.

Who Should Consider PRF?

PRF is ideal for individuals who want a natural, subtle improvement in their appearance. It’s particularly beneficial for those looking to:

  • Improve skin texture and tone

  • Reduce fine lines and wrinkles

  • Address under-eye hollows

  • Enhance overall skin quality

 

Since PRF doesn’t add immediate volume like fillers, it may not be the best choice for people seeking a dramatic change. However, it’s an excellent option for individuals interested in organic, gradual skin rejuvenation.

Each of these options has unique benefits, and the choice depends on individual goals and preferences.

  • Radiesse offers immediate volume and is excellent for lifting and contouring.

  • Sculptra provides gradual volume through collagen stimulation and is ideal for long-lasting results.

  • Hyaluronic Acid fillers work instantly, offering flexibility for areas like the lips and under the eyes.

  • PRF offers a natural, gradual improvement, perfect for subtle rejuvenation, especially under the eyes.

  • PRP is a similar option to PRF, with a faster but shorter-lasting effect.

 

For those seeking a natural, long-term improvement without synthetic fillers, PRF might be the best option. If you’re considering aesthetic treatments, consult with a professional to find out which solution aligns best with your goals and desired results.

Natural Rejuvenation

PRF is a completely natural way to refresh areas that show early signs of aging. It uses parts of your own blood, making it a gentle alternative to chemical treatments. 

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We can use PRF as a filler, in special healing injections, as a serum with SkinPen treatments, and more!

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It works especially well for under-eye circles, fine lines, and dark spots.

References

Wu, Qing-Yun1; Zhang, Qian2; Fang, Fang2,*; Bu, Wen-Bo2,*. Clinical Application of Platelet-Rich Fibrin in Dermatology. International Journal of Dermatology and Venereology 5(3):p 160-165, September 2022. | DOI: 10.1097/JD9.0000000000000186

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